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My father has had this small pimple-like spot biopsied, frozen, cut, etc. 4 times since February. This last time, it was diagnosed as cancer. How was it not 3 previous times? Well, in one month it has gone from the size of a nickel to a crater about 4 inches across. Growing rapidly, weeping constantly, very painful. I can't cover it because of the size and because he's developed an adhesive allergy. Plastic Surgery said it's too large to remove in office (it was about 2 inches across when they said that) and he will need surgery with general anesthesia a minimum of 2 hours while they check margins and create a skin graft. He is still mobile, engaged with family, an avid reader, pretty easy to care for in spite of AD. This, I never saw coming. It needs treatment because it is so painful and is causing him distress to see in the mirror. Anyone know other treatments we could try? I really want to avoid general anesthesia. They said sedation was not an option. Has anyone else experienced this? His overall health is good.

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It appears your concern is general anesthesia. Being in the anesthesia profession and having a mother with dementia, I understand your concern I would ask to speak to the anesthesia provider about your concerns. The elderly under general anesthesia do well with total IV anesthesia (propofol), local and a little narcotic. Sedation is not an option because the area is on the face and will be a larger incision with the surgery taking several hours.
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Reply to Kaysmile10
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I cannot speak to the dementia component of this, but will relate on the skin graft. My dad had the same type of skin cancer, squamous cell, and had the surgery using a skin graft from his thigh. He was in his mid 80’s at the time. Though the surgery went fine, the recovery was a true nightmare. Both sites healed slowly and poorly, taking about a full year. Neither ever looked close to normal again. There was lots of oozing, redness, and discomfort. Dad became so discouraged. I regretted he’d ever agreed to it. I wish your dad a much smoother recovery if it’s decided to go forward
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Reply to Daughterof1930
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sp196902 Jul 13, 2024
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https://www.amazon.com/Leukoplast-Elastic-Fabric-Adhesive-Bandages/dp/B0BPVHQ738
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Reply to RetiredBrain
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Do the surgery. Your Dad is still reading. He has very, very early dementia.
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Geaton777 Jul 11, 2024
My 100-yr old Aunt with advanced dementia could read anything and everything but she wasn't processing the words. The ability to read does not mean there's a higher level of cognition in operation.
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My wife had general anesthesia for breast cancer following a brain bleed about 3 years earlier. The angst and/or surgery caused her dementia to become significantly worse. But the cancer tumors could have killed her. She made the decision to have the surgery. We are very happy that the tumors were removed and that she will get to enjoy her newest grandchild.
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Reply to MikeinTexas
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Not sure why sedation is not an option. Ask about conscious sedation - he will not be on a ventilator, but receive enough medication to help him relax and not feel pain.
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my2cents Jul 11, 2024
Yes. And general anesthesia could be on stand by if needed. Explain situation to dr
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Ask the Drs what they advise for the pain. I ate to be blunt, however Alzheimer’s is a death sentence. You just need to make how much time he has left comfortable.

It sounds like a fairly major surgery. I don’t have first hand knowledge, however I’ve heard that can really be a set back with Alzheimer’s and what you lose you don’t get back.

See if surgery is the only way to alleviate pain or if Dr can suggest something else.
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Reply to Donttestme
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I'm 87--much older than OP's parents if I read the profile correctly. I would probably opt for the surgery to deal with the pain and disfigurement. Both of these would be a real drag on quality of (remaining) life--for me. At my age I likely would not agree to chemo or radiation due to the side effects. If I were 60-something, however, I might make a different decision. I would definitely inquire about palliative care and hospice.
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Reply to ElizabethAR37
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Is the lesion still squamous cell carcinoma? (Has it become melanoma; keytruda was developed for melanoma.) Who is treating him? Dermatologist or another medical professional? I had a sizeable squamous cell carcinoma on my back which was removed with local anesthesia by UTSW dermatologist. The margins were checked THEN, not later. I did not have general anesthesia.
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Geaton777 Jul 7, 2024
To clarify:

"Squamous cell cancer cannot turn into melanoma since each type of cancer arises from different types of cells in the skin. It is possible, however, to have both squamous cell skin cancer and melanoma skin cancer at the same time."

Source: https://www.emedicinehealth.com/does_squamous_cell_cancer_turn_into_melanoma/article_em.htm
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The cancer is painful and distressing: that alone will cause your father's health to decline, including his mental health.

So, yes, anaesthesia will likely cause some progression of his dementia, but treatment would bring him some relief.

There is always a risk of death when undergoing anaesthesia, even for a young and healthy person. In my early 40s, I stopped breathing during surgery and was at risk of not waking up. The alternative to surgery was becoming paralyzed. The risk was worth it.
There is risk with so many things in life; they can't all be avoided.

If it were my decision to make, I would opt for my parent to have the surgery and have a chance of being comfortable in their last years. There is no comfort or peace to be had with a painful, weeping cancerous wound.
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Anxietynacy Jul 7, 2024
I was thinking the same thing, and also I would definitely shut down and talk of chemo or radiation, really quick.
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KimberlyO: Pose your questions to his oncologist.
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Reply to Llamalover47
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Have you gotten a second opinion? Sometimes you will find specialists have differing opinions on treatment and or experience with AD patients that might help you with this decision.
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Reply to Lymie61
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My 80-year father had a two-hour double hernia surgery under general anesthesia. He has dementia and was even more confused for a solid week after surgery, but it had to be done because he put the surgery off for over five years due to his wife being ill and dying. He was in a lot of physical pain. We were very concerned with general anesthesia too, but dad recovered well considering the dementia symptoms.
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Reply to Joyful13
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You need to decide on the presence of value and quality of life. Clearly pain is a symptom that needs to be treated to continue quality of life. You do not mention his level of dementia. For dressings, you will need to speak to a wound specialist who will know about types of dressings that are out there.
You probably should go with the surgery knowing that there may be some delerium and decline. In his case his pain needs to be taken care of. Hope for the best!
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Reply to MACinCT
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I get from this article it should be removed. It can be cured if found early.

Adhesive...I can not wear the old white stuff. There is paper tape and hypo-allergetic tape.

https://healthsea.com/squamous-cell-carcinoma/
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Reply to JoAnn29
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My cousin aged 69 got it on his nose. It got huge he had it removed but did nothing else, he died 4+ years later from it, did ok until the very end. He had mild dementia.
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Reply to MeDolly
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Given that he seems to be in the very early stages of dementia and is therefore many years away from dying from Alzheimer's I would go for the surgery if that is the only/best option given, especially since this is causing symptoms that are negatively affecting his QOL now and into the immediate future.
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Reply to cwillie
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"Although squamous cell carcinoma can be more aggressive than basal cell cancer, the risk of this type of cancer spreading is low—as long as the cancer is treated early...the lesions must be treated with respect because they may grow rapidly and invade deeply."

Source: https://www.yalemedicine.org/conditions/squamous-cell-carcinoma#:~:text=Although%20squamous%20cell%20carcinoma%20can,grow%20rapidly%20and%20invade%20deeply.

You don't say where the lesion is, but sounds like it may be on his face. Close to his brain and lymph nodes? Has any of his doctors checked to see if it has spread? If not, why not? If so and it's only that lesion, then there may be other treatment options.

Options include:
Excisional surgery.
Mohs surgery.
Cryosurgery.
Curettage and electrodesiccation (electrosurgery)
Laser surgery.
Radiation.
Photodynamic therapy (PDT)
Topical medications.

"In June 2020, pembrolizumab (Keytruda®) was approved by the FDA for the treatment of recurrent or metastatic SCC that is not curable by radiation or surgery. In July 2021, the FDA expanded this approval to include SCC that is locally advanced and not curable by radiation or surgery."

Source: https://www.skincancer.org/skin-cancer-information/squamous-cell-carcinoma/advanced-scc/#:~:text=Treatment%20overview&text=In%20June%202020%2C%20pembrolizumab%20(Keytruda,curable%20by%20radiation%20or%20surgery.
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Grandma1954 Jul 2, 2024
A friend of mine, her husband has LBD / Parkinson's and he was put on Keytruda for a skin cancer. Made the dementia much worse they discontinued the Keytruda. May be an isolated incident but it would be something that I would look into.
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This is a tough call mainly because you said it is causing him pain. And it is distressing for him.
If the doctors think he will get through the surgery alright that is half the battle.
Do know that he will probably decline due to the anesthesia. It is not a "death sentence" but you never know how much the anesthesia will effect him. He may be fine, it may take a week to get back to "baseline" or a month or he may not return to his pre surgery cognition.
So as much as I am normally for minimizing medical procedures I think in this case I would opt for the surgery.
Recovery will be difficult mainly because he is going to want to not keep his hands off the area. And it will look worse before it gets better and that may upset him as well.
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